Renal denervation: back to reality, finally!

Renal Denervation

Type 2 diabetes mellitus (T2DM) is a group of metabolic diseases of multiple etiologies. Although great progress has been made, researchers are still working on the pathogenesis of T2DM and how to best use the treatments available. Aside from several novel pharmacological approaches, catheter-based sympathetic renal denervation (RDN) has gained a significant role in resistant hypertension, as w...

Business process verification - finally a reality!

ion rule Fusion of equivalent nets rule Elimination of self-loop transition rule Fig. 8. Reset Reduction rules (Please note that the figure does not capture all the requirements for some rules (i.e., if a transition cannot have a reset arc (double-headed arc) or a place cannot be reset, the figure will not show this.)

Renal Denervation to Treat Cardiac Fibrosis?

H ypertension is extremely common across the world, and substantial resistance to pharmacological therapy occurs in a considerable subset, possibly >10% of afflicted patients. The morbid consequences or comorbidities associated with hypertension are extensive and range from renal failure to myocardial infarction. For the most part, these comorbidities are more common with resistant hypertension...

Renal denervation in moderate to severe CKD.

Sympathetic activation contributes to the progression of CKD and is associated with adverse cardiovascular outcomes. Ablation of renal sympathetic nerves reduces sympathetic nerve activity and BP in patients with resistant hypertension and preserved renal function, but whether this approach is safe and effective in patients with an estimated GFR (eGFR) < 45 ml/min per 1.73 m(2) is unknown. We p...

Ruminations About Renal Denervation.